In March, 1838, in company with his father and his brother Harvey, Anson started to Missouri, whither some of the leading Elders of the Church had already gone. They journeyed by steamboat part of the way, and had for companions Asahel Smith, uncle to the prophet, and George Gee and their wives. While steaming up the Missouri river they were accosted by a fellow passenger who remarked that he had heard there were some "Mormons" on board the boat. Elder Smith told him the rumor was correct, and that he and his companions were "Mormons." The stranger then inquired to what part they were going, and was informed that Far West was their destination. "I am sorry to see such a respectable looking company journeying to that place," was the rejoinder. Being asked why he felt sorry, he said: "Because you will be driven from there in less than six months." "By whom" was asked. "By the Missourians, gentlemen," he replied, and then added, "I presume you are not aware of the gentlemen you are talking to." "Yes, gentlemen," was the response, "I am Colonel Wilson, of Jackson County. I was one of the principal actors in driving the "Mormons" from that country, and I expect to be soon engaged in driving them from Caldwell County." He strongly advised them to stop in some other place and not to venture into Caldwell County, declaring if they did so they would certainly be butchered; for "Mormonism" must and shall be put down. He read a letter to the brethren which he said he had just received from Randerson Newell. He was reminded that it was made up of falsehoods concerning the Saints in Kirtland, and replied "True or false, Joe's career must and shall be stopped!" As he turned to depart after this last remark Anson Call said to him, "If you will wait a moment I will tell you the way it can be done, for there is but one way." "What is that, sir?" the Missourian sharply demanded. "Dethrone the Almighty, and Joseph Smith's career will be ended, and never will it be until then." The steamer stopped at Jefferson City, and Anson was there introduced by Colonel Wilson to a dozen or so of the "Jackson County boys," the notorious Governor Boggs among the number. When informed that Mr. Call was a "Mormon" on his way to Caldwell County, they indulged in a sneering laugh. The boat proceeded to Jack's Landing, where the company left the river. Anson and his father traveled on foot from there to Far West. They afterwards purchased land in Caldwell County upon which to establish homes, and then the father returned to Ohio, to make arrangements for the removal to Missouri. In July, 1838, Anson started towards Ohio and met his family journeying to Missouri. After resting and visiting a few days in Far West he settled his family on his farm on Grand river, being accompanied by Phinears H. Young, John Snider, Joel Terry and others.