General Anatomy, Applied to Physiology and Medicine, Vol. 1 (of 3)Bichat, Xavier
Science
General Anatomy, Applied to Physiology and Medicine, Vol. 1 (of 3)
Bichat, Xavier
Human anatomy; Human physiology
Are the nerves reproduced when they have been cut? The experiments of
many distinguished anatomists evidently prove that they are. What is
the manner of this reproduction? If we examine the results of these
experiments it is easy to see that there is nothing peculiar in the
nervous system, that it is a simple cicatrization analogous to the
callus of bones, to the cicatrix of the skin, &c. When a nerve has
been cut, its two ends inflame, the cellular texture that it contains
sends forth granulations by the property of reproduction that it
possesses. These granulations meeting, form adhesions that unite the
two divided ends of the nerve. As the cellular texture, the means of
union, grows from the cut extremity of the nervous coat, as well as
from that which is between the cords, it partakes of the nature of
the nervous coat, and becomes a parenchyma of nutrition, whose mode
of organic sensibility is analogous to that of the nerves, and whose
vessels deposit there medullary substance, which gives a new appearance
to the nervous cicatrix, and makes it resemble very nearly the texture
of the nerves themselves. However, as the granulations arising from
the divided ends are not made in a regular manner, there is never at
the place of union a thread-like arrangement as there is in the nerve
itself. Thus the callus of a long bone, though analogous to this bone,
is never regularly arranged like it in longitudinal fibres; thus a
cutaneous cicatrix has always an irregularity in its organization,
which arises from the irregular manner in which the parenchyma of
cicatrization has been developed.
The cicatrization of nerves is then analogous to that of bones. In
the first period there is inflammation; in the second, growth of the
cellular texture which is to serve for the nutritive parenchyma; in
the third, adhesion of those parts that have grown; in the fourth,
exhalation of the medullary substance into the parenchyma. It is
this medullary substance that makes this cicatrix differ from the
osseous, in which phosphate of lime and gelatine are deposited, from
the muscular, in which there is fibrin, &c. Sometimes there is an
enlargement in the form of a ganglion, at the place of the reunion of
the nerves; this depends upon the greater granulation of the cellular
texture. Thus sometimes the callus is enlarged; at others, if the
contact has been exact, we perceive but a slight difference; these are
varieties that do not affect the nature of cicatrization.
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