Moreover, the character of the glandular life of which we are treating, is only an insulated modification of a character general to all the vital properties, a character which consists in this, that they are weakened in one place when they are raised in another. Hence why the great collections of pus, large tumours and dropsies are always attended with a weakness in the glandular action. It is upon this character that rests the use of vesicatories, setons, moxa, cauteries, &c. which do not act, as has been said, by evacuating the morbific matter, but by making the irritation of the diseased part cease by that which is produced elsewhere. _Fourth Character. Influence of climate and season on Glandular Life._ Another phenomenon is also derived from the preceding character, and it is one that may be likewise considered as characteristic of the glandular system; viz. that in general it is in greater activity in winter than summer, in cold climates than in warm. In fact, heat which expands the cutaneous system increases the action of it at the expense of that of the glands, and reciprocally cold which contracts it, by preventing the constant exhalation that is going on there, forces the glandular system to supply this action. Hence why the same fluid, introduced into the economy, goes out with the urine in winter and with the sweat in summer; why, if we wish to produce an immediate discharge of urine in summer, it is necessary to suppress the perspiration by the sudden application of cold to the surface of the skin, by descending into a cellar, or some other subterraneous place; so that in summer we can, after digestion, make the product of the fluids pass off with the urine or the sweat, according to the temperature of the atmosphere in which we digest; why teas and diuretics forbid the use of each other, and why a physician who should employ them at the same time would know but little of the laws of our economy; why most of the diseases that are attended with an immoderate discharge of the secreted fluids, are almost always characterized by a diminution of the exhaled fluids; why in some seasons diseases have a greater tendency to be characterized by sweats, and in others by urinary, mucous evacuations, &c. It is to the greater degree of the vital activity of the glandular system in the winter, that must then be referred the frequency of catarrhs, diseases most of which suppose an unnatural increase of its action, the greater facility with which the kidneys are influenced by cantharides, &c. Physicians should have these considerations particularly in view in their treatment. It is necessary to act more upon the glandular system in winter, and the cutaneous in summer, because each system is as much more disposed to answer to the excitements made upon it, as it actually is in greater activity. _Fifth Character. Influence of Sex upon Glandular Life._