Gout, with a section on ocular disease in the goutyLlewellyn, Llewellyn J. (Llewellyn Jones)
Science
Gout, with a section on ocular disease in the gouty
Llewellyn, Llewellyn J. (Llewellyn Jones)
Eye -- Diseases; Gout
Old gouty subjects are often of sallow or parchment-like complexion.
The _blood_ in these cases of polyarticular gout conforms in attenuated
degree, in the matter of leucocytosis and secondary anæmia, to that
observed in the more _acute_ types, as witness the following blood
pictures.
All were males, the subjects of chronic articular gout of many
years’ standing. They all exhibited _tophi_, which were verified
microscopically. The examinations were conducted during the
inter-paroxysmal periods.
(1) BLOOD COUNT.
Red corpuscles, per c. mm. 4,832,000 = 96·6 per cent.
Hæmoglobin = 64 ”
Colour index = ·66 ”
Leucocytes, per c. mm. 11,000
DIFFERENTIAL COUNT.
Lymphocytes 42 = 4,620
Large mononuclears 4 = 440
Polymorphonuclears 52·5 = 5,775
Eosinophils 0 = 0
Mast cells 1·5 = 165
(2) BLOOD COUNT.
Red corpuscles, per c. mm. 5,040,000 = 100·8 per cent.
Hæmoglobin = 72 ”
Colour index = 0·72 ”
Leucocytes, per c. mm. 13,400
DIFFERENTIAL COUNT.
Lymphocytes 15 = 2,010
Large mononuclears 2·5 = 335
Polymorphonuclears 78 = 10,452
Eosinophils 1 = 134
Mast cells 3·5 = 469
(3) BLOOD COUNT.
Red corpuscles, per c. mm. 4,280,000 = 85·6 per cent.
Hæmoglobin = 66 ”
Colour index = 0·77 ”
Leucocytes, per c. mm. 12,000
DIFFERENTIAL COUNT.
Lymphocytes 23 = 2,760
Large mononuclears 3 = 360
Polymorphonuclears 74 = 8,880
Eosinophils 0 = 0
Mast cells 0 = 0
In these chronic forms, save during exacerbations, there may be little or
no febrile movement, and local pain, heat, and redness may be slight or
wholly lacking. But the articular swellings never wholly disappear, and
the mobility of the joints is never entirely regained. The articulations,
few or many, become stiff, ankylosed, and deformed, by the growth of
_tophaceous deposits_. But to detailed description of these latter we
shall return later.
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