The ulceration usually commences with a small vesicle on the membrane, which after a few days bursts, leaving a small unhealthy ulcer, which has no disposition to heal, but, on the contrary, gradually spreads and deepens. The nostril first affected by discharge is generally first affected by ulceration. After the formation of ulcers the discharge is often tinged with blood, and becomes offensive. 3d. The submaxillary gland, in the channel formed between the lower jaw-bones, becomes swollen and painful, but, as a rule, shows no inclination to suppurate. It soon becomes hard and firmly attached to the jawbone, and ceases to be painful on the application of pressure. On any one of the above-enumerated symptoms appearing, at once isolate the animal; have bedding destroyed, and carefully remove all clothing, stable utensils, etc., from the vicinity of other horses. Place a steady man in charge, and warn him of his personal danger. GREASE. =Symptoms.=--A diseased state of the skin of the legs, more especially the hind ones, caused by uncleanliness or washing with cold water and not properly drying them afterwards. In the early stages it consists of intolerable itching, followed by an inflammation of the sweat-glands, and an offensive oily discharge. The heels feel hot and greasy. =Treatment.=--Trim hair; poultice with warm bran and charcoal for several days, changing twice a day, and cleaning with sponge and tepid water each time; or apply a flaxseed poultice over which has been poured some lotion consisting of sugar of lead ½ oz., carbolic acid 1 drachm, water 1 quart. Then, if animal is not weak, give a dose of purgative medicine, and when it has acted apply to the heels a dressing of vaseline 1 oz., oxide of zinc 2 drachms, iodized phenol 20 drops; or equal parts of sulphate of zinc and sugar of lead in water; or carbolic acid 1 part, glycerine 20 parts, applied with a brush and covered with lint and bandage, is good after poulticing. When the frog is affected, pare to the quick and dress with dry caustic powders (quicklime, copperas, bluestone) or carbolic acid, and put on tight bandage, the dressing being renewed every day at least. When there is any tendency to inflammation or ulceration of skin of heels in bad weather, dress with lard or tallow, or lard 8 parts and alum 1 part. HIDE-BOUND. =Symptoms.=--The hide becomes tightly drawn over the flesh, and the coat hard and staring. =Treatment.=--Aloes 1½ oz., sulphur 3½ oz., ginger ½ oz., linseed-meal ½ oz. Make into six balls, and give one night and morning. HOOF-BOUND. =Symptoms.=--This is the result of some preceding disease of the foot, giving rise to an atrophy of the flesh structures of the foot, allowing the wall to fall in and become contracted. =Treatment.=--Stand in moist place; apply blistering liquid (powdered cantharides 1 part, olive-oil 6 to 8 parts) to coronet.