It is well to observe, that neither in these nor in other poison-eaters is there the least trace of an arsenic cachexy discernible; that the symptoms of a chronic arsenical poisoning never show themselves in individuals who adapt the dose to their constitution, even although that dose should be considerable. It is not less worthy of remark, however, that when, either from inability to obtain the acid, or from any other cause, the perilous indulgence is stopped, symptoms of illness are sure to appear, which have the closest resemblance to those produced by poisoning from arsenic. These symptoms consist principally in a feeling of general discomfort, attended by a perfect indifference to all surrounding persons and things, great personal anxiety, and various distressing sensations arising from the digestive organs, want of appetite, a constant feeling of the stomach being overloaded at early morning, an unusual degree of salivation, a burning from the pylorus to the throat, a cramp-like movement in the pharynx, pains in the stomach, and especially difficulty of breathing. For all these symptoms there is but one remedy—a return to the enjoyment of arsenic. According to inquiries made on the subject, it would seem that the habit of eating poison among the inhabitants of Lower Austria has not grown into a passion, as is the case with the opium-eaters in the East, the chewers of the betel nut in India and Polynesia, and of the coco-leaves among the natives of Peru. When once commenced, however, it becomes a necessity. In some districts sublimate of quicksilver is used in the same way. One case in particular is mentioned by Dr. von Tschudi, a case authenticated by the English embassador at Constantinople, of a great opium-eater at Brussa, who daily consumed the enormous quantity of forty grains of corrosive sublimate with his opium. In the mountainous parts of Peru the doctor met very frequently with eaters of corrosive sublimate; and in Bolivia the practice is still more frequent, where this poison is openly sold in the market to the Indians.