It has been asserted by some that very large doses of strychnine are directly antidotal to snake venom, but more recent experience does not tend to confirm this view; still there is no harm in making the trial, and if the services of someone capable of giving the injections can be secured, the treatment is certainly worth the trial. The immediate injection into the tissues around the wound of a one-per-cent. watery solution of chromic acid or potassium permanganate is thought to be of value by destroying the poison, but in order to be efficient it must be administered within a short time after the bite has been received. Should the patient's condition become serious, and the breathing finally stop, artificial respiration may be resorted to. As soon as the remedies suggested have been tried, it is time for us to go back to the ligature, which cannot be suffered to remain around the limb indefinitely, as by cutting off the blood-supply it will sooner or later produce death of the tissues. From time to time we should slowly loosen the bandage, thus allowing a little of the poison to pass into the body, and at the same time permit the entrance of a small quantity of blood into the tissues of the limb beyond the ligature; the bandage should of course be tightened at the end of a half a minute, and it should be alternately loosened and tightened every half hour until the patient is considered to be out of danger. The reader cannot fail to have observed that nothing has been said concerning the use of alcohol in the treatment of snake-bite, and the matter is only here referred to for the purpose of condemning it as being unsound in theory and bad in practice.