"Claudere quae caenas lactuca solebat avorum Dic mihi cur nostras inchoat illa dapes." Antoninus Musa cured Caesar Augustus of hypochondriasis by means of this plant. The most common variety of the wild Lettuce, improved by frequent cultivation, is the Cabbage Lettuce, or Roman, "which is the best to boil, stew, or put into hodge-podge." Different sorts of the Cos Lettuce follow next onwards. The _Lactuca sylvatica_ is a variety of the wild Lettuce producing similar effects. From this a medicinal tincture (H.) is prepared, and an extract from the flowering herb is given in doses of from five to fifteen grains. No attempt was made to cultivate the Lettuce in this country until the fourth year of Elizabeth's reign. When bleached by gardeners the lettuce becomes tender, sweet, and succulent, being easily digested, even by dyspeptic persons, as to its crisp, leafy parts, but not its hard stalk. It now contains but little nutriment of any sort, but supplies some mineral salts, especially nitre. In the stem there still lingers a small quantity of the sleep-inducing principle, "lactucarin," particularly when the plant is flowering. Galen, when sleepless from [310] advanced age and infirmities, with hard study, took decoction of the Lettuce at night; and Pope says, with reference to our garden sort:-- "If you want rest, Lettuce, and cowslip wine:--'probatum est.'" But if Lettuces are taken at supper with this view of promoting sleep, they should be had without any vinegar, which neutralises their soporific qualities. "Sleep," said Sir Thomas Brown, "is so like death that I dare not trust it without my prayers." Some persons suppose that when artificially blanched the plant is less wholesome than if left to grow naturally in the garden, especially if its ready digestibility by those of sensitive stomachs be correctly attributed to the slightly narcotic principle. It was taken uncooked by the Hebrews with the Paschal lamb. John Evelyn writes enthusiastically about it in his _Book of Sallets_: "So harmless is it that it may safely be eaten raw in fevers; it allays heat, bridles choler, extinguishes thirst, excites appetite, kindly nourishes, and, above all, represses vapours, conciliates sleep, and mitigates pain, besides the effect it has upon the morals-- temperance and chastity."