On and after Monday, February 28, this road will be open for business throughout its entire length. Passenger trains will leave St. Joseph for Hannibal every morning, making close connection with steam packets to St. Louis and Quincy, and affording direct connection with all the railroads east of the Mississippi river. Time from St. Joseph to Hannibal, eleven hours, and to St. Louis, eighteen hours, saving more than three days over any other route. Trains from the east will arrive in St. Joseph every evening, connecting with a daily line of packets running between St. Joseph and Kansas City; also a line up the Missouri to the Bluffs. Passengers from all parts of Kansas will find this the quickest and most agreeable route to St. Louis and all points on the Mississippi, giving those going east a choice between the routes from St. Louis, Alton and Quincy. Fare will be as low as by any other route. Favorable arrangements will be made for taking freight, saving most of the heavy insurance on the Missouri river. Express freight will be taken through much quicker than by any other line. Tickets can be had at the office in St. Joseph for nearly all parts of the country. JOSIAH HUNT, Sup’t. P. B. GROAT, Gen’l. Ticket Ag’t. Feb. 1st, 1859. no. 48–lm. (From _Freedom’s Champion_, Atchison, February 12, 1859.) HANNIBAL & ST. JOSEPH RAILROAD. NEW ROUTE OPEN FOR THE EAST AND SOUTH. Passengers for St. Louis, northern Missouri, Iowa, Chicago, Cincinnati, Detroit, Boston, New York, Philadelphia, Baltimore, New Orleans, Louisville and Southern States, will find this the shortest, quickest and most desirable route to the above points. On the 1st day of February only fifteen miles of staging intervenes between St. Joseph and Hannibal, and on the 1st day of March, 1859, the road will be completed, and open for through travel the entire length. A daily line of stages from Atchison, passing through Doniphan and Geary City, connects at St. Joseph with the H. & St. Jo. railroad. From Hannibal a daily line of packets leave upon arrival of cars for St. Louis, upon the opening of navigation, and boats connect at Quincy with the C. B. & Q. railroad for Chicago, and with the G. W. railroad for Toledo via Naples. This is in every respect the best route for eastern and southern passengers. Trains leave St. Joseph for the east daily. JOSIAH HUNT, Sup’t. P. B. GROAT, General Ticket Agent. (no. 47) (From _Freedom’s Champion_, Atchison, February 12, 1859.) THE FIRST TELEGRAPH.