1849, finally settled the more important questions connected with the sexual theory about the same time that Hofmeister established the microscopic embryology of Phanerogams on a firm foundation. Other parts also of vegetable physiology had been considerably advanced before 1840; Theodore de Saussure observed in 1822 the production of heat in flowers and its dependence on respiration; ten years later Goeppert proved the rise of temperature in germinating and vegetating organs. Dutrochet stimulated enquiry by his researches in various branches of the science between 1820 and 1840; he was the first to apply the phenomena of diosmosis to the explanation of the movement of sap in plants with a lasting influence on the further progress of physiology. Chemical investigations were less fruitful in results, though they served to collect a considerable material of single facts, which could afterwards be turned to theoretical account. The close of this period, which began with unprofitable doubts, but in which much was set in a train for further development after 1840, is marked by the publication of some important compilations, in which all that had as yet been done in vegetable physiology was presented in a connected form. In addition to Dutrochet’s collected works (1837) three comprehensive compendia of vegetable physiology made their appearance, one by De Candolle, which was translated into German by Roeper and published with many improvements and additions in 1833 and 1835; this was followed by a work on vegetable physiology by L. C. Treviranus, 1835-1838, and lastly by Meyen’s ‘Neues System der Pflanzenphysiologie,’ 1837-1839. These works exhibit the characteristic features of the period chiefly in this, that physiology finds as yet no strong support in phytotomy, while the old views of vital force are brought face to face with more exact physico-chemical explanations of processes of vegetation.