Political influences, however, favoured the spread of the new doctrine. It had been the dream of Henry VII., as it was also the dream of his son and successor, to strengthen England at the expense of France, by bringing about an alliance and if possible a union between England and Scotland. It was in furtherance of this design that Henry VII. had given his eldest daughter in marriage to James IV., who was slain with most of his nobles in a battle with the English on the fatal field of Flodden (1513). The schemes for a union with Scotland were continued by Henry VIII., particularly after his rupture with Rome had shown him the danger that might be anticipated from the north in case the French or the Emperor should declare war in defence of the Church. A regular contest began at the Scottish court between the friends of Rome and of France and the agents of Henry VIII., the latter of whom took care to encourage those who favoured religious innovations. The queen-mother, sister of Henry VIII., and many of the nobles favoured the plans of Henry, who sought to induce the King of Scotland to join him in the struggle against Rome, and who promised him in return for this service the hand of his daughter the Princess Mary and the friendship of the English nation. James V., backed by the bishops and encouraged by messengers from Rome, refused to come south for a conference with Henry VIII., or to give any countenance to the schismatical policy of his uncle. As a sign that Scotland was still true to France he married the daughter of Francis I. of France (1537), and on her death shortly after her arrival in Scotland, he took as his second wife (1538) Mary of Guise, daughter of the Duke of Guise and sister of the Cardinal of Lorraine.[5] He was ably assisted in his struggle against heresy and English interference by David Beaton, Archbishop of St. Andrew's (1539-46) and a cardinal of the Roman Church. The latter was at once a churchman and a politician, loyal to Rome and to France, earnest in his defence of Scottish independence, and determined to defeat the English schemes against both the religion and liberty of Scotland. As friendly remonstrances and invitations failed to produce any effect, Henry VIII. determined to have recourse to war. He felt that he could rely upon the assistance or the neutrality of many of the Scottish nobles whom he had won over to his side, and soon events showed that this confidence was not misplaced. The Scottish army was put to a shameful flight at Solway Moss, probably more by treachery than by the cowardice of the Scottish nobles, and James V. was so heartbroken by the news of this disaster that he died in a few weeks (Dec. 1542) leaving behind him an infant daughter, to be known later as Mary Queen of Scots.