“Three separate series of experiments were made by Doctors Mohler and Rosenau. Young cattle and sheep were inoculated with vaccine virus obtained from both firms. Foot and mouth disease was produced in experimental animals by the use of vaccine of the same strain obtained from both sources, while other strains of vaccine tested gave negative results. The disease was also transmitted from one animal to another through several series, in two instances by natural modes of infection. “The investigation also indicates that the outbreaks of foot and mouth disease in New England in 1902-3 were probably due to contaminated vaccine of Japanese origin from the Mulford Company.... “The fact that the infection was present in the vaccine virus of the Mulford Company for so long a period, but was not transmitted to outside cattle, was doubtless due to this firm’s practice of killing its calves after taking the vaccine virus. Parke, Davis & Co., on the other hand, rented their calves and placed them again on the market a short time after the vaccine material was taken. In this way the disease spread from the vaccine stables of Parke, Davis & Co., but not from those of the Mulford Company, although it was the vaccine virus from the latter establishment that infected the former’s cattle.... “As soon as the facts regarding the contamination of vaccine became known, the licenses of the two firms involved were at once suspended, all the suspected vaccine virus on hand was destroyed and that upon the market withdrawn, and other measures of a radical nature were taken. The report commends the intelligent and prompt coöperation of the Mulford Company and Parke, Davis & Co. in accomplishing this end. After an examination of every strain of vaccine upon the market, it is stated that there is now (1909) upon the market no vaccine contaminated with the virus of foot and mouth disease. Regulations have been formulated with a view to preventing hereafter the propagation of contaminated vaccine virus. No instance of the transmission of foot and mouth disease to man through vaccine virus has been recorded, and it is considered doubtful, in view of the tests made, if it is possible to reproduce the disease in him by the cutaneous inoculation commonly used in the process of vaccination.” AN OFFICIAL DOUBT DISPROVED