_First_: The lockjaw germs may be in the virus itself and be inoculated directly into the vaccination wound at the moment of vaccination. And, despite Dr. Anderson’s negative tests, the possibility of this direct infection can exist at any time, as admitted by some of our best authorities, already quoted, on account of the many ways in which the infection can enter the virus, from the vaccinated calf itself and otherwise, and also because its presence cannot always be proved by tests, although known to be in the virus. The lockjaw germ normally dwells in and issues from the digestive organs of domestic animals and is therefore found in manure and garden soil and on the hide and hair of animals and hence may be in the body of the vaccinated calf itself from which the virus is produced! _Second_: The lockjaw germ, which is widely distributed in some localities, may exist on the person of the vaccinator or the vaccinated at the time of vaccination and be then introduced into the wound with the virus, and the two infections may thus develop together, the pus infection in the wound being necessary to “activate” the lockjaw germs as already shown. _Third_: The lockjaw germ may enter the vaccination wound and grow in its pus secretion at any time during its suppurating stage by chance scratching, abrasion or absorption, and thus develop its awful toxin with fatal effect on the vaccinated victim. _Fourth_: The lockjaw germ may already exist within the body when the vaccination is performed, and is known to frequently exist as a natural tenant or denizen of the healthy human body, in nearly one-quarter of the human race! This is also the case with several other disease germs. In such cases the indwelling lockjaw germ will remain entirely inert, dormant and harmless in the body unless some condition necessary to its “activation” or growth is presented, such as that of a suppurating sore, ulcer, abscess or wound, anywhere within or upon the body, the pus-infected or suppurating vaccination sore being, of course, the ideal condition for the activation and growth of the fatal lockjaw infection, as already shown; and this is probably the most common and dangerous way in which vaccination can cause death from lockjaw and other diseases, and the greatest care in the preparation of the virus itself cannot avoid this danger!