The greed of alcohol for water causes it to imbibe moisture from the tissues and juices, and to inflame the delicate mucous membrane. It shows the power of Nature to adapt herself to circumstances, that the soft, velvety lining of the throat and stomach should come at length to endure the presence of a fiery liquid which, undiluted, would soon shrivel and destroy it. In self-defense, the juices pour in to weaken the alcohol, and it is soon hurried into the circulation. Before this can be done, "it must absorb about three times its bulk of water"; hence, very strong liquor may be retained in the stomach long enough to interfere seriously with the digestion, and to injure the lining coat. Habitual use of alcohol permanently dilates the blood vessels; thickens and hardens the membranes; in some cases, ulcerates the surface; and, finally, "so weakens the assimilation that the proper supply of food can not be appropriated." --FLINT. [Footnote: The case of St. Martin (p. 168) gave an excellent opportunity to watch the action of alcohol upon the stomach. Dr. Beaumont summarized his experiments thus: "The free, ordinary use of any intoxicating liquor, when continued for some days, invariably produced inflammation, ulcerous patches, and, finally, a discharge of morbid matter tinged with blood." Yet St. Martin never complained of pain in his stomach, the narcotic influence of the alcohol preventing the signal of danger that Nature ordinarily gives.] EFFECT UPON THE LIVER.--Alcohol is carried by the portal vein directly to the liver. This organ, after the brain, holds the largest share. The influence of the poison is here easily traced. "The color of the bile is soon changed from yellow to green, and even to black;" the connective tissue between the lobules becomes inflamed; and, in the case of a confirmed drunkard, hardened and shrunk, the surface often assuming a nodulated appearance known as the "hobnailed liver." Morbid matter is sometimes deposited, causing what is called "Fatty degeneration," so that the liver is increased to twice or thrice its natural size.