POISONOUS MILK, CHEESE, AND ICE CREAM (p. l69).--In late years there have been many cases of poisoning by ice cream, cheese, and milk. The poisonous principle sometimes developed in these articles of food has been made a subject of special investigation, and it has been found to be due to natural causes. Dr. Vaughan, of Michigan, after spending several months in experimenting upon samples of twelve different cheeses, which had caused three hundred cases of poisoning, finally succeeded in isolating certain poison crystals, which he calls _Tyrotoxicon_. He says: "A few drops of an aqueous solution of these crystals placed upon the tongue produces all the symptoms observed in those who had been made sick by eating of the cheese. This was tried repeatedly upon myself, and upon some of my students who kindly offered themselves for experimentation." Dr. Vaughan afterward procured the poison crystals from milk which had stood some months in a closed bottle, and also from a sample of ice cream by which eighteen persons had been made ill. It was learned in the latter case that the custard, of which the ice cream was made, had been allowed to stand in a foul atmosphere for two hours before it was frozen. By placing small bits of this poisonous cream in good milk, and allowing it to stand twenty-four hours, the whole became vitiated. This proved that the poison is due to the growth of some ferment. In the autumn of 1886, many persons in different hotels at Long Branch were poisoned by milk obtained from a certain milkman. In this case it was found that the cows were milked at noon, the warm milk being immediately placed in cans and carted eight miles during the warmest part of the day, in a very hot month. In June, 1887, nineteen persons in New York city were similarly poisoned by milk which also came from one dairy. Many of these persons had narrow escapes from death. These, and many other like instances, teach us the importance of the greatest care in every detail of milk handling. A little dried milk formed along the seam of a tin pail, or any similar lodging place, may be the starting point of poison generation. A month after his first experiments with the ice cream mentioned above, Dr. Vaughan put small pieces of the dried custard in pans of milk, and afterward made custard from this milk. This yielded tyrotoxicon as before, showing the tenacious vitality of the poison, and also explaining the fact that the precise cause of poisoning is in many cases so difficult to trace.