Here and there we find a constitution upon which opium exerts few or none of its characteristic effects. Such cases are, of course, wholly exceptional; but their very existence is a danger to others, misleading them into the idea that they may dally with the tempter without falling under its yoke, or may fall under that yoke and find it a light one. I doubt, however, whether the most fortunate of its victims would encourage the latter idea; whether there be an opium eater who would not give a limb never to have known what opium slavery means....Besides, no one can be sure, or indeed reasonably hope, that the mischief will be confined to the individual victim. That the children of drunkards are often predisposed to insanity is notorious; that the children of habitual opium eaters inherit an unmistakable taint, whether in a diseased brain, in morbid cravings, or simply in a will too weak to resist temptation, is less notorious, but equally certain.--PERCY GREG, _Narcotics and Stimulants, Contemporary Review_. Thus also in America scarcely a week passes but we see announced in the public prints deaths or suicides resulting from the use of narcotics. Now, it is from tobacco: A Yale College student dies from excessive smoking; another student in the same college, and as a result of the same habit, commits suicide; a third young man is found dead in his bed in New York, from heart disease induced by cigarettes; and so, month by month, and year by year, grows in rapid increase the list of tobacco deaths.--Or, again, it is from opium. A Harvard student with two of his college companions in search of a new sensation, tries opium smoking one fatal night and dies before morning; a woman in Ohio, belonging to a prominent family, dies at the age of thirty-three years, from an overdose of morphine, her body covered with hypodermic scars; another, once the respected wife of a Baptist clergyman, becomes a morphine drunkard, drifts, step by step, into a Central New York Almshouse, and there hangs herself; a third, young, accomplished, and wealthy, falls first a victim to the morphine habit, then to opium smoking, finally becomes the frequenter of a New York opium joint, and so is lost forever to home, friends, and respectability.-- Occasionally it is cocaine, as in the case of the Chicago physician, who, for the purposes of investigation, experiments with this new drug upon himself, his wife, and finally upon his innocent children; the entire family being found unconscious from the effects of the subtle narcotic. These are but solitary instances in an appallingly long list of similar cases, most of which have occurred within the last two years (1887-'88).