We learned on page 55 what a peculiar office the membrane fills in nourishing the organs it enwraps. Anything that disturbs its delicate structure must mar its efficiency. Alcohol has a wonderful affinity for water. To satisfy this greed, it will absorb moisture from the tissues with which it comes in contact, as well as from their lubricating juices. The enlargement of the blood vessels and their permanent congestion must interfere with the filtering action of the membrane. In time, all the membranes become dry, thickened, and hardened; they then shrink upon the sensitive nerve, or stiffen the joint, or enfeeble the muscle. The function of these membranes being deranged, they will not furnish the organs with perfected material, and the clogged pores will no longer filter their natural fluids. Every organ in the body will feel this change. EFFECT UPON THE BLOOD. [Footnote: Alcohol acts upon the oxygen carrier, the coloring matter of the red corpuscles, causing it to settle in one part of the globule, or even to leave the corpuscle, and deposit itself in other elements of the blood. Thus the red corpuscle may become colorless, distorted, shrunken, and even entirely broken up--Dr. G. B. HARRIMAN.]-- From the stomach, alcohol passes directly into the circulation, and so, in a few minutes, is swept through the entire system. If it be present in sufficient amount and strength, its eager desire for water will lead it to absorb moisture from the red corpuscles, causing them to shrink, change their form, harden, and lose some of their ability to carry oxygen; it may even make them adhere in masses, and so hinder their passage through the tiny capillaries.--RICHARDSON. With most persons who indulge freely in alcoholic drinks, the blood is thin, the avidity of alcohol for water causing the burning thirst so familiar to all drinkers, and hence the use of enormous quantities of water, oftener of beer, which unnaturally dilutes the blood. The blood then easily flows from a wound, and renders an accident or surgical operation very dangerous. When the blood tends, as in other cases of an excessive use of spirits, to coagulate in the capillaries, [Footnote: The blood is rendered unduly thin, or is coagulated, according to the amount of alcohol that is carried into the circulatory system. "The spirit may fix the water with the fibrin, and thus destroy the power of coagulation; or it may extract the water so determinately as to produce coagulation. This explains why, in acute cases of poisoning by alcohol, the blood is sometimes found quite fluid, at other times firmly coagulated in the vessels."--B. W. RICHARDSON.]