An arrangement has been made with the Miamies for the cession of a part of their reservation in the State of Indiana. The tracts held by them are far more extensive than they require; and as they appear to be not yet prepared for removal, this relinquishment, without injuring them, will relieve the State, in some measure, from the embarrassment caused by such large reservations as they possess, embracing a most valuable part of the country, and interrupting the settlements and communication. Instructions were given, immediately after the last session of Congress, for purchasing from the Wyandots in Ohio, if they were disposed to sell, the reservation secured to them in that state, and for their removal to the west. The commissioner, Governor Lucas, conducted the negotiation with great fairness and propriety, fully explaining to the Indians their own position, the wishes of the government, and the course of circumstances urging their removal. The matter is not yet terminated, the Indians having requested time for further consideration. The necessary appropriations will be asked for the removal of the Seminoles, agreeably to the treaty formed with them; and arrangements have been made for the emigration of the Creeks, as fast as they are prepared for a change of residence. There has not yet been sufficient time to ascertain the result of these measures. I am not able to submit to you any more favourable views of the condition of the Cherokees than were embraced in my last annual report. While every dictate of prudence, and, in fact, of self-preservation, urges their removal, unhappy councils and internal divisions prevent the adoption of that course. Where they are, they are declining, and must decline; while that portion of the tribe which is established in the west, is realizing the benefits which were expected to result from a change of position. The system of removal, however, by enrolment, is going on, and during this season about one thousand persons have passed to the west. The treaty concluded the 24th of May last, with the Chickasaws, has altered the relations in which they were placed with the United States. The proceeds derivable from a portion of their present possessions have been assigned to them, and reservations have also been provided for such as choose to become citizens of the United States. Their future condition now depends upon their own views and experience, as they have a right to remain or remove, in conformity with their own judgment. The means placed at their disposal are fully adequate to their permanent comfortable establishment, and it is to be sincerely hoped that they will apply them wisely.