_Turpentine oil._.—Turpentine oil is a peculiar-smelling, colourless
liquid of the composition C₁₀H₁₆; different reactions show that
turpentine oil contains the aromatic nucleus (cymene). It is used in
the manufacture of varnish, and thus can cause industrial poisoning
by inhalation of fumes. Even from 3 to 4 mg. of vapour of turpentine
oil per litre of air brings on severe symptoms. Turpentine oil acts as
a local irritant, and when absorbed into the system has an exciting
effect upon the central nervous system. Inhalation of large quantities
of turpentine vapour cause rapid breathing, palpitation, giddiness,
stupor, convulsions, and other nervous disturbances, pains in the chest,
bronchitis, and inflammation of the kidneys. The last-mentioned symptom
also arises from the chronic action of turpentine vapours.
_Pyridine._—Pyridine (C₅H₅N), a colourless liquid of peculiar odour, is
employed as well as methylalcohol in denaturing alcohol. The disturbance
of health observed in workers occupied with the denatured spirit are
probably mainly due to the inhalation of fumes of methylalcohol. Pyridine
is comparatively innocuous. Eczema, from which persons suffer who
come into contact with denatured spirit, is ascribed to the action of
pyridine. Larger doses produce a paralysing effect, but this need not be
considered in its industrial use.
_Nicotine, tobacco._—According to various published statements, effects
among tobacco factory workers are attributed to the nicotine contained
in tobacco dust and to the aroma which fills the air. Nicotine in large
doses has at first an exciting followed by a paralysing effect upon the
central nervous system; it causes moreover contraction of the unstriped
muscles and has a local irritant effect.
The symptoms of illness ascribed to nicotine are: conjunctivitis, catarrh
of the air passages, palpitation, headache, want of appetite, and,
particularly, tendency to abortion and excessive menstruation. Severe
industrial poisoning due to nicotine has only been observed in workers
who chewed tobacco leaves.
_Poisonous wood._—The symptoms of disease noticed in workers who
manipulate certain kinds of wood are attributed by some writers to the
presence of alkaloids. Such knowledge as we have of the illness due to
them—they are evidently of the nature of poisoning—is referred to at the
end of Part I.
PART III
_PREVENTIVE MEASURES AGAINST INDUSTRIAL POISONING_
I
_GENERAL MEASURES_
In discussing preventive measures against industrial poisoning the
deductive method from the general to the particular will be followed. The
numerous instances of poisoning mentioned in Part I afford a practical
basis on which to formulate general rules before passing on to describe
special measures. Technical details will be omitted, as they must be left
to the technical expert whose business it is to draw up the plans as a
whole and to modify them according to the requirements of individual
cases.
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