The same results were obtained. This time six cubic centimeters were administered to each individual. Finally, transfer was made directly with swabs from the nose, throat and nasopharynx of one individual to another in nineteen cases. None developed the disease. The next series of experiments consisted in an attempt to inoculate volunteers with influenza by injecting into them 10 cc. of citrated blood, which was the pooled collection from five cases of acute influenza. Ten volunteers were inoculated. None took sick. Next, the secretions from the upper respiratory tract of acute cases were injected subcutaneously into ten volunteers, each receiving 3.5 cc. This material was first put through a porcelain filter. None took ill. In an attempt to reproduce the disease in imitation of nature, ten individuals were exposed to cases of acute influenza in hospital wards. Each volunteer was placed very near to the patient, shook hands with him, talked and chatted with him, for five minutes, after which he received the patient’s breath full in his face five times while he inhaled, and finally the patient coughed five times directly into the subject’s face. Each volunteer did this with each of ten different patients, all of them acutely ill, none more than three days sick. No volunteers developed the disease. All cases of influenza used throughout the period of these experiments were typical acute cases selected from a distinct focus or outbreak of the disease. Sometimes, for example, they would select four or five typical cases from an epidemic in a school with a hundred cases. In February, 1919, the experiments were continued at Portsmouth, where the secretions were transferred direct from individual to individual. In about thirty-six hours half of the number came down with streptococcus sore throat, but not with influenza. One of the medical officers, however, who had been very active in the experiments, and who had come into intimate contact with the disease since early in October, but who had not been inoculated, developed, during this experiment, typical influenza. The explanation for these failures is not certain. The experiments were started rather late after the onset of the epidemic, and the volunteers may have developed some immunity, although they had not developed the disease. Or, they may never have been susceptible. McCoy made a similar series of experiments in San Francisco, using volunteers who so far as known had not even been exposed to the outbreak, also with negative results. However, many of these latter had been “vaccinated against influenza” with a mixed vaccine.