Influenza : $b An epidemiologic studyVaughan, Warren T. (Warren Taylor)
History
Influenza : $b An epidemiologic study
Vaughan, Warren T. (Warren Taylor)
Influenza
After the 1889–1893 epidemics, Leichtenstern recorded that the mortality
tables of all countries agree in showing considerable rise in the
mortality from pulmonary tuberculosis in influenza periods. The
clinicians of that time made the frequent observation that the course of
tuberculosis in the lungs is markedly and unfavorably influenced by grip
and its pneumonic complications. Latent quiescent cases often became
active, and healed and healing foci broke out anew. Afebrile cases were
changed to the hectic type and frequently hemoptysis was induced. In
London, during the height of the 1889 epidemic, the weekly death reports
from phthisis rose to double the average. The increase in death rate
during the epidemic period was not limited entirely to tuberculosis, but
there was almost a doubling of deaths due to all acute respiratory
infections. After the cessation of the epidemic, however, there was some
decrease in the general mortality, as well as in the mortality from
respiratory infections. This was especially true of deaths from
pulmonary tuberculosis, which decreased to such an extent that the total
mortality rate for the year for this disease was little greater than for
preceding years.
Similar observations have been made following the 1918 pandemic. Jordan
remarks that in New York City in 1918 during the two weeks of maximum
epidemic mortality, the deaths reported from pulmonary tuberculosis
numbered 430, as compared with 264 for the corresponding weeks of 1917.
Vaughan and Palmer found that the deaths from tuberculosis in the army
were higher in the autumn of 1918 than in the two previous four months’
periods, the death rate rising from 18 per 100,000 during the summer to
46 per 100,000 in the autumn. The rate for the same time of the
preceding year had been 15 per 100,000. They assume that the most
plausible explanation for this increase in deaths is that dormant and
incipient cases introduced into the army during the preceding year had
accumulated and possibly were hastened into the acute stage, both by the
duties of camp life, and the prevalence of the epidemic of grip and
pneumonia. Quite naturally there had been from the time of the first
assembling of troops an accumulation of tuberculous individuals,
inasmuch as such men were not discharged, but were kept in the army and
under Government control and supervision. Sir Arthur Newsholme in
reviewing the relationship between influenza and tuberculosis in England
concludes that many deaths from tuberculosis are undoubtedly hastened
during an influenza epidemic. Abbott wrote of the epidemic of 1889 in
Massachusetts that the chief diseases which followed in its train and
were intimately associated with it were bronchitis and pneumonia, and
that phthisis when already existing in the victim of the attack was
undoubtedly aggravated, and in many cases a fatal termination was
hastened. Baldwin says that influenza is a frequent and important agent
in bringing latent tuberculosis to life.
Public-domain text, read in full here on John Shaqi.
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