While in the corresponding months of 1915–1916 the deaths attributed to influenza were 957 The deaths attributed to pneumonia in December, 1914, and January, 1915, were 1,468 While the number of deaths attributed to the same cause in December, 1915, and January, 1916, were 2,563 Coffey and others have reported an epidemic of influenza at Worcester, Mass. during the first three weeks of January, 1916. During the first three weeks of January, 1915, there were reported in that city twenty-two deaths from respiratory diseases, making a total of 14.9 per cent. of the total deaths. In the same period of 1916 there were reported ninety-three deaths from acute respiratory diseases in the same population. Two of the more complete descriptions of the epidemic of the year 1915–16 are those by Mathers, and by Capps and Moody. Mathers reports that: “During the winter of 1915–1916 the United States was visited by a severe epidemic of acute respiratory infections which resembled in every detail the great epidemic of 1890. This outbreak was apparently first noticed in the Middle Western States, and it spread rapidly over the entire country, taking a heavy toll of human life. December and January were the months in which these infections were most prevalent, and the epidemic had almost completely lost its impetus by March, 1916. During the height of this epidemic in Chicago, sixty-one cases of the disease were studied bacteriologically, and the results form the basis of this paper.” Mathers found hemolytic streptococci in forty-six instances, in all of which they predominated. Green producing streptococci were found thirty times, with one pure culture, and pneumococci thirty times with four pure cultures. Staphylococci were isolated in fifty cases; Micrococcus catarrhalis in six, and Friedländer’s bacillus in one case. The influenza bacillus was found in only one instance, and then in small numbers. The majority of the patients were studied early in the course of the disease, and in the earliest, hemolytic streptococci were almost constantly found, especially in the throat. In the atypical pneumonia which followed many of the attacks of grip, hemolytic streptococci predominated. In none of these was the Bacillus influenza found. Mathers reported that coincident with the epidemic among humans there was an epizootic of so-called influenza among horses. The symptoms are very similar to that of the disease among humans. He isolated a streptococcus as the predominating organism in the horses. The streptococci from human and equine sources, although similar in many characteristics, differed widely in pathogenicity, and seemed to be highly parasitic for the specific hosts. Capps and Moody found that in man most cases began rather abruptly, with coryza, pharyngitis, laryngitis, or bronchitis.