From this subjection it is but a short step to the acquisition of co-ordinations which express themselves as movements newly acquired by the individual,” and, “The integrating power of the nervous system has, in fact, in the higher animal more than in the lower, constructed from a mere collection of organs and segments a functional unity, an individual of more perfected solidarity,” also “a single momentary shock produces in the nervous arc a facilitating influence on a subsequent stimulus applied even 1400σ later.” I will give but one more statement from this work which seems to tell against my humble position of initiative in evolution. Professor Sherrington says at the end of his book, speaking of the adjustments of nervous reactions in the lifetime of the individual: “These adjustments though not transmitted to the offspring yet in higher animals form the most potent internal condition for enabling the species to maintain and increase in sum its dominance over the environment in which it is immersed.” A little care in reading the foregoing chapters will show that this in no way contradicts the views expressed. Facilitation. From Professor Starling’s Principles of Human Physiology I may again quote part of his account of Facilitation or “Bahnung.” “When an impulse has passed through a certain set of neurones to the exclusion of others it will tend, other things being equal, to take the same course on a future occasion, and each time it traverses this path the resistance in the path will be smaller. Education is the laying down of nerve-channels in the central nervous system, while still plastic, by the process of ‘Bahnung’ along fit paths combined with inhibition (by pain) in the other unfit paths. Memory itself has the process of facilitation for its neural basis,” again, “stimulation of one anterior root produces no definite movement of a group of muscles, but partial contraction of a number of muscles which do not normally contract simultaneously. Thus, stimulation of a sensory nerve may provoke either flexion or extension of a limb, not both simultaneously. Stimulation of the motor roots will cause simultaneous contraction of both flexor and extensor muscles. It is _this subordination of morphological to physiological arrangements_ in the limbs which has necessitated the foundation of limb-plexuses.” (Italics not in the original). Professor Graham Kerr in his work on Embryology before mentioned says: “In early stages of Evolution, whether phylogenetic or ontogenetic, we may take it that vital impulses flitted hither and thither in an indefinite manner within the living substance and that one of the features of progressive evolution has been the gradual more and more precise definition of the pathways of particular types of impulse, as well as the transmitting and receiving centres between which they pass. We may then regard the appearance of neuro-fibrils within the protoplasmic