So long as the race remains radically the same, the stringent selection of the best specimens to rear and breed from, can never lead to any permanent result. The attempt to raise the standard of such a race is like the labour of Sisyphus in rolling his stone uphill; let the effort be relaxed for a moment, and the stone will roll back. Whenever a new typical centre appears, it is as though there was a facet upon the lower surface of the stone, on which it is capable of resting without rolling back. It affords a temporary sticking-point in the forward progress of evolution. The causes that check the unlimited improvement of highly-bred animals, so long as the race remains unchanged, are many and absolute. In the first place there is an increasing delicacy of constitution; the growing fineness of limb and structure end, after a few generations, in fragility. Overbred animals have little stamina; they resemble in this respect the "weedy" colts so often reared from first-class racers. One can perhaps see in a general way why this should be so. Each individual is the outcome of a vast number of organic elements of the most various species, just as some nation might be the outcome of a vast number of castes of individuals, each caste monopolising a special pursuit. Banish a number of the humbler castes--the bakers, the bricklayers, and the smiths, and the nation would soon come to grief. This is what is done in high breeding; certain qualities are bred for, and the rest are diminished as far as possible, but they cannot be dispensed with entirely. The next difficulty lies in the diminished fertility of highly-bred animals. It is not improbable that its cause is of the same character as that of the delicacy of their constitution. Together with infertility is combined some degree of sexual indifference, or when passion is shown, it is not unfrequently for some specimen of a coarser type. This is certainly the case with horses and with dogs. It will be easily understood that these difficulties, which are so formidable in the case of plants and animals, which we can mate as we please and destroy when we please, would make the maintenance of a highly-selected breed of men an impossibility.