Pepsin.—My experiments are hardly worth giving, as it is scarcely
possible to prepare pepsin free from other albuminoids; but I was
curious to ascertain, as far as that was possible, whether the ferment
of the secretion of Drosera would act on the ferment of the gastric
juice of animals. I first used the common pepsin sold for medicinal
purposes, and afterwards some which was much purer, prepared for me by
Dr. Moore. Five leaves to which a considerable quantity of the former
was given remained inflected for five days; four of them then died,
apparently from too great stimulation. I then tried Dr. Moore’s pepsin,
making it into a paste with water, and placing such small particles on
the discs of five leaves that all would have been quickly dissolved had
it been meat or albumen. The leaves were soon inflected; two of them
began to re-expand after only 20 hrs., and the other three were almost
completely re-expanded after 44 hrs. Some of the glands which had been
in contact with the particles of pepsin, or with the acid secretion
surrounding them, were singularly pale, whereas others were singularly
dark-coloured. Some of the secretion was scraped off and examined under
a high power; and it abounded with granules undistinguishable from
those of pepsin left in water for the same length of time. We may
therefore infer, as highly probable (remembering what small quantities
were given), that the ferment of Drosera does not act on or digest
* ‘Leçons phys. de la Digestion,’ 1867, tom. ii., p. 304. [page 124]
pepsin, but absorbs from it some albuminous impurity which induces
inflection, and which in large quantity is highly injurious. Dr. Lauder
Brunton at my request endeavoured to ascertain whether pepsin with
hydrochloric acid would digest pepsin, and as far as he could judge, it
had no such power. Gastric juice, therefore, apparently agrees in this
respect with the secretion of Drosera.
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