Certain tendencies characteristic of the science of our day clearly suggest the direction of our thoughts most appropriate to the occasion. Among the strongest of these is one toward laying greater stress on questions of the beginning of things, and regarding a knowledge of the laws of development of any object of study as necessary to the understanding of its present form. It may be conceded that the principle here involved is as applicable in the broad field before us as in a special research into the properties of the minutest organism. It therefore seems meet that we should begin by inquiring what agency has brought about the remarkable development of science to which the world of to-day bears witness. This view is recognized in the plan of our proceedings, by providing for each great department of knowledge a review of its progress during the century that has elapsed since the great event commemorated by the scenes outside this hall. But such reviews do not make up that general survey of science at large which is necessary to the development of our theme, and which must include the action of causes that had their origin long before our time. The movement which culminated in making the nineteenth century ever memorable in history is the outcome of a long series of causes, acting through many centuries, which are worthy of especial attention on such an occasion as this. In setting them forth we should avoid laying stress on those visible manifestations which, striking the eye of every beholder, are in no danger of being overlooked, and search rather for those agencies whose activities underlie the whole visible scene, but which are liable to be blotted out of sight by the very brilliancy of the results to which they have given rise. It is easy to draw attention to the wonderful qualities of the oak; but from that very fact, it may be needful to point out that the real wonder lies concealed in the acorn from which it grew. Our inquiry into the logical order of the causes which have made our civilization what it is to-day will be facilitated by bringing to mind certain elementary considerations--ideas so familiar that setting them forth may seem like citing a body of truisms--and yet so frequently overlooked, not only individually, but in their relation to each other, that the conclusion to which they lead may be lost to sight. One of these propositions is that psychical rather than material causes are those which we should regard as fundamental in directing the development of the social organism. The human intellect is the really active agent in every branch of endeavor,--the _primum mobile_ of civilization,--and all those material manifestations to which our attention is so often directed are to be regarded as secondary to this first agency. If it be true that "in the world is nothing great but man; in man is nothing great but mind," then should the keynote of our discourse be the recognition of this first and greatest of powers.