Irritability : $b a physiological analysis of the general effect of stimuli in living substanceVerworn, Max
Science
Irritability : $b a physiological analysis of the general effect of stimuli in living substance
Verworn, Max
Irritability
ectoplasm of the cell body interfere with strong mechanical stimuli
in such a manner that a negative thigmotaxis develops; following weak
mechanical stimuli a positive thigmotaxis results. Here is an instance
of the relation between the intensity of the stimulus and the manner in
which its effects interfere with an already existing excitation.
[Illustration:
_A_ _B_ _C_
Fig. 41.
Thigmotaxis of Paramaecium aurelia.]
However, the strength of the inhibitory effect of a weak contact
stimulus upon another excitation is best appreciated when positive
thigmotaxis is interfered with by the effect of a thermal or galvanic
stimulus. _Jennings_[165] and especially _Pütter_[166] have, at my
request, more thoroughly investigated my original observations and
have given us a complete analysis of these interesting interference
effects. If the freely swimming Paramecia are subjected to a constantly
increasing temperature, the movements of these infusoria become more
and more active. At 30° C., the rapidity is very violent and at
about 37° C. they reach their maximal. If now the same experiment is
repeated with Paramecia which have in consequence of thigmotaxis fixed
themselves to particles of slime, the temperature may be increased to
30° C. without an observable effect. The infusoria remain throughout
in contact with the resistance. Only when the temperature is 37° C.
do they release their contact and move violently through the water.
If a drop containing Paramecia is placed on a slide, between parallel
pieces of fired clay which serve as electrodes, it will be seen that
some freely swim about, whereas others remain thigmotactically in
contact with particles of slime. When a constant current of about .2
of a milliampère is passed through, it is observed that the freely
swimming individuals hasten towards the cathode. Those attached
to objects, on the contrary, do not respond in this manner to the
electrical current. (Figure 42.) The intensity of the current can be
greatly increased without bringing about detachment of the individuals
from their position of fixation. The typical influence of the strong
current upon the movement of the cilia of the thigmotactically fixed
individuals can be clearly seen. Nevertheless, the inhibition, brought
about by the contact stimulus, predominates over that of the excitating
effect of the current, so that a freeing of the organisms from their
position does not occur. Not until the current becomes very strong is
the excitation thereby produced sufficient to bring about a separation
of the infusoria, whereupon they immediately swim toward the cathode.
In this interference between the contact stimulus, on the one hand,
and the thermal or galvanic on the other, the inhibitory effect of the
former may overpower the strong excitation of the latter.
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