Irritability : $b a physiological analysis of the general effect of stimuli in living substanceVerworn, Max
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Irritability : $b a physiological analysis of the general effect of stimuli in living substance
Verworn, Max
Irritability
The question here follows: Is there a _constancy of this interruption
of the equilibrium of rest produced by the stimulus_ which can be
formulated into a general law? To begin with, the number of possible
responses are greater than the variety of forms of living substance,
for every living organism with its specific properties can undergo
alteration in its metabolism in various directions. Thereby results an
infinite number of manifold reactions to stimuli. However, in answer to
the question, in which direction the change in the specific metabolism
of rest in response to a stimulus takes place, we find a comparatively
simple scheme of general reaction. All phenomena can change in their
rapidity as well as in their nature. That is quantitatively and
qualitatively. In this way the specific vital process of an organism
can be altered by the stimulus, on the one hand, in its rapidity; on
the other, in the manner of its action.
The majority of all temporary responses to stimuli consist in
_alterations of rapidity of the vital process_, and form either a
quickening or retardation of its course. The former is manifested in a
strengthening or an increase, the latter in a decrease or repression
of the specific action of the living organism. The stimuli have the
same effect as in the case of the catalysers in chemical processes.
According to _Ostwald’s_[43] well-known definition of catalysis
a catalyser is a substance which, without appearing in the final
product of a chemical reaction, alters its rapidity. This group of
reactions can, therefore, be referred to as “_catalytic stimulation and
response_.” When the response consists in _increase_, we speak, in a
physiological sense, of an excitation, and when there is decrease in
the vital processes, we speak of a depression.
[43] _Ostwald_: “Ueber Katalyse.” Verhandl. d. Ges. Deutscher Naturf.
und Aerzte zu Hamburg 1901.
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