"That this may be our happy experience, is the fervent desire of your sincere and affectionate friend, "ISAAC T. HOPPER. "NEW-YORK, 4th mo. 15, 1852." Early in the Spring, he was conveyed to the house of his daughter, Mrs. Gibbons, in the upper part of the city; it being supposed that change of air and scene might prove beneficial. It was afterward deemed imprudent to remove him. His illness was attended with a good deal of physical suffering; but he was uniformly patient and cheerful. He often observed, "There is no cloud. There is nothing in my way. Nothing troubles me." His daughters left all other duties, and devoted themselves exclusively to him. Never were the declining hours of an old man watched over with more devoted affection. Writing to his daughter Mary, he says: "I have the best nurses in New-York, thy mother and sisters. I have every comfort that industry and ingenuity can supply." Among the Quakers who manifested kindness and sympathy, several belonged to the branch called Orthodox; for a sincere respect and friendship had grown up between him and individuals of that Society, in New-York, after the dust of controversy had subsided. He was always glad to see them; for his heart warmed toward the plain dress and the plain language. But I think nothing during his illness gave him more unalloyed satisfaction than a visit from William and Deborah Wharton, Friends from Philadelphia. He loved this worthy couple for their truly Christian character; and they were, moreover, endeared to him by many tender and pleasant associations. They stood by him generously during his severe pecuniary struggles; they had been devoted to his beloved Sarah, whose long illness was cheered by their unremitting attentions, and she, for many years, had received from Hannah Fisher, Deborah's mother, the most uniform kindness. William's father, a wealthy merchant, had been to him an early and constant friend; and his uncle, the excellent mayor of Philadelphia, had sustained him by his influence and hearty co-operation, in many a fugitive slave case, that occurred in years long past. It was, therefore, altogether pleasant to clasp hands with these tried and trusty friends, before life and all its reminiscences faded away. His physician, Dr. John C. Beales, was very assiduous in his attentions, and his visits were always interesting to the invalid, who generally made them an occasion for pleasant and animated conversation; often leading the doctor off the professional track, by some playful account of his symptoms, however painful they might be. He had been his medical adviser for many years, and as a mark of respect for his disinterested services to his fellow-men, he uniformly declined to receive any compensation.