We have seen, then, that up to the year 1645 the ancestor-cult had been tolerated by the Jesuits [338] in China, with promising results; and it is probable that an identical policy of tolerance was maintained in Japan during the second half of the sixteenth century. The Japanese missions began in 1549, and their history ends with the Shimabara slaughter in 1638,--about seven years before the first Papal decision against the tolerance of ancestor-worship. The Jesuit mission-work seems to have prospered steadily, in spite of all opposition, until it was interfered with by less cautious and more uncompromising zealots. By a bull issued in 1585 by Gregory XIII, and confirmed in 1600 by Clement III, the Jesuits alone were authorized to do missionary-work in Japan; and it was not until after their privileges had been ignored by Franciscan zeal that trouble with the government began. We have seen that in 1593 Hideyoshi had six Franciscans executed. Then the issue of a new Papal bull in 1608, by Paul V, allowing Roman Catholic missionaries of all orders to work in Japan, probably ruined the Jesuit interests. It will be remembered that Iyeyasu suppressed the Franciscans in 1612,--a proof that their experience with Hideyoshi had profited them little. On the whole, it appears more than likely that both Dominicans and Franciscans recklessly meddled with matters which the Jesuits (whom they accused of timidity) had been wise enough to leave alone, and that this interference hastened the inevitable ruin of the missions.