Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and PancreasHarley, George
Science
Jaundice: Its Pathology and Treatment: With the Application of Physiological Chemistry to the Detection and Treatment of Diseases of the Liver and Pancreas
Harley, George
Jaundice
The first and great object is, of course, as in the case of every other
disease, to remove, if possible, the exciting cause. When that is
accomplished, we can with safety turn our attention to the removal of
its effects. I need not here detail the different exciting causes which
it is our duty to remove. I have indicated them elsewhere, and the mere
mention of some of their names is sufficient to denote the line of
treatment which ought to be adopted. Thus, for example, if it be {102}
ascertained from there being symptoms of tenderness, &c., in the
hepatic region, that the jaundice arises from active congestion of the
liver, the first object would of course be to subdue the congestion of
that organ by means of leeches, hot fomentations, saline purgatives,
&c., according to the age, sex, and constitution of the patient. On the
other hand, if the jaundice be the result of passive congestion of the
liver, we know well that so long as the exciting cause exists
elsewhere, it will be worse than futile to attempt the removal of the
hepatic congestion by direct means. In such a case, therefore, if to
remedy the cause is beyond our power, our object will be to concentrate
our efforts on the mitigation of its effects. Thus I might go through
the whole list of causes of jaundice, and point out what appears to be
the most appropriate treatment of each; but I think the time of my
readers and my space, will be more profitably employed, if, instead of
doing so, I turn my remarks chiefly to the therapeutical action of
those remedies which we are constantly employing in the treatment of
jaundice. The first remedy that merits special notice is mercury.
The benefit of mercury in cases of liver disease cannot be denied; but
the injudicious employment of this drug in cases of jaundice, has
frequently been followed by the most disastrous results. {103} There
was a time when mercury was administered in all cases of jaundice,
irrespective of their cause; now, however, men are fortunately becoming
more careful in the employment of this drug. But there is still a
mistaken notion regarding the therapeutical action of mercurial
preparations. It was at one time thought that they stimulated the liver
to secrete bile, and now since physiology has shown that they possess
no such action, many have gone to the opposite extreme, and declared,
that if mercurials do not stimulate the liver to secrete bile, their
benefit in hepatic disease has been a delusion; and the dark stools
following upon their employment but the result of the sulphuret of
mercury formed in the intestines. I take a very different view of the
matter; for though believing that mercury does not directly stimulate
the liver to secrete bile, I nevertheless opine that it has an
important indirect effect in reinducing the biliary secretion, and
thereby curing certain cases of jaundice.
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