So it assuredly was: so probably under the circumstances must any passion for a woman have been. Stroke on stroke of untoward fortune had in truth begun to fall on Keats, as if in fulfilment of the constitutional misgivings of his darker moods. First the departure of his brother George had deprived him of his chief friend, to whom almost alone he had from boyhood been accustomed to turn for relief in hours of despondency. Next the exertions of his Scotch tour had over-taxed his strength, and unchained, though as yet he knew it not, the deadly hereditary enemy in his blood. Coming back, he had found the grasp of that enemy closed inexorably upon his brother Tom, and in nursing him had lived in spirit through all his pains. At the same time the gibes of the reviewers, little as they might touch his inner self, came to teach him the harshness and carelessness of the world's judgments, and the precariousness of his practical hopes from literature. Last were added the pangs of love--love requited indeed, but having no near or sure prospect of fruition: and even love disdained might have made him suffer less. The passion wrought fiercely in his already fevered blood; its alternations of doubt and torment and tantalising rapture sapped his powers, and redoubled every strain to which bereavement, shaken health, and anticipations of poverty, exposed them. Within a year the combined assault proved too much for his strength, and he broke down. But in the meantime he showed a brave face to the world, and while anxiety gnawed and passion wasted him, was able to throw himself into the labours of his art with a fruitful, if a fitful, energy. During the first few weeks of winter following his brother's death, he wrote indeed, as he tells Haydon, "only a little now and then: but nothing to speak of--being discontented and as it were moulting." Yet such work as Keats did at this time was done at the very height of his powers, and included parts both of _Hyperion_ and _The Eve of St Agnes_.