But even within our own times how greatly has general ignorance retarded the exertions of medical science to diminish suffering and to reduce the amount of mortality! The prejudices against vaccination have rendered it extremely difficult to eradicate small-pox, however certain the result of the great discovery of Jenner. According to the present law, all children, born in England and Wales after August 1, 1853, _must_ be vaccinated at the public expense. Such a law would have been very difficult of execution twenty years ago. The people had then seen the scarred faces from small-pox disappearing amongst them. They had learnt that, at the beginning of this century, vaccination, or the puncture of the skin with matter originally obtained from the cow, was rooting out the small-pox, which used to destroy, not more than a hundred years ago, thirty-six thousand persons annually, in this kingdom. But yet they had prejudices. No medical man would practise inoculation--a great blessing in its day--because the disease was thus kept amongst us. But still many ignorant persons did not avail themselves of the law passed fourteen years ago, under which their children _might_ be vaccinated at the public cost. The undoubted testimony of the whole medical profession proves that vaccination in almost all cases prevents small-pox, and in all cases mitigates its evil. But that testimony further proves that if vaccination were universal, small-pox would wholly disappear; and that is the reason why vaccination is now compulsory.