There are many theories regarding the possible exciting causes of navicular disease and, when one has carefully considered the explanations as offered by Peters, Moeller, Branell, Schrader and others, he may conclude that navicular disease is a non-infectuous inflammatory affection of the third sesamoid (navicular) bone, deep flexor tendon (perforans) and adjoining structures. Whether it originates in the flexor tendon or whether the bone is the original part affected, the disease is frequently met, and of all possible causes, jars and irritation incident to concussion of travel, are probably the principal causative agents. Symptomatology.--Lameness is the primary indicator and a constant symptom which attends navicular disease wherever much structural change affects the infirm parts. As the degree of intensity or extent varies, so is there a dissimilarity in the character of the impediment. Incipient cases of bilateral involvement are more difficult to diagnose than are unilateral affections, particularly when lameness is not marked. There is manifested a supporting-leg-lameness which varies as to degree in the same subject at different times. This may be noticed during the same trip in an animal that is being driven. There is a tendency for the subject to stumble and, of course, where the affection is bilateral, there is a stilted gait owing to shortened strides. At rest the lame animal usually points with the affected member. Because of the fact that the distance is lessened between the origin and insertion of the deep flexor tendon (perforans) by this attitude, one may readily understand the reason for the position assumed by the subject. Pressure on the navicular bone is diminished and tension on the flexor tendon is relieved by even slight volar flexion. In acute inflammatory affections abnormal heat may be detected in the region of the heel. By exerting tension on the flexor tendon, by means of passive dorsal flexion of the member, evidence of hyperesthesia may be detected. With the hoof testers one may determine supersensitivenss in most instances. There occurs more or less contraction of the hoof in navicular disease, but this is not to be taken as a cause of the affection, but rather a sequence. [Illustration: Fig. 32--"Pointing"--the position assumed by horse having unilateral navicular disease.] In some cases of unilateral navicular disease there is a marked contrast in size between the sound and unsound foot. However, one must not be misguided in this particular, for in some pairs of sound feet there exists considerable difference in size. Finally, by a change from the normal position of the foot to one in which the heel is somewhat elevated (as may be obtained by shoeing with high heel calks), relief is evident, and in the opposite position, the condition is aggravated. This experiment may be used for diagnostic purposes.