Thus it is seen that because of its frequent communication with the other parts of this large synovial membrane, a wound which opens the external portion of the femerotibial capsule may be the cause of contamination and resultant infectious arthritis of the whole stifle joint. Because of the distance between the most dependent part of the femerotibial articulation and the summit of the patella, one may misjudge the exact location of the lowermost part of this portion of the capsular ligament of the stifle joint and thereby fail at once to appreciate the seriousness of calk wounds in this region. Etiology and Occurrence.--Wounds to the patellar region are of rather frequent occurrence, and because of the comparatively unprotected position of these structures, the capsular ligaments of the stifle joint may be perforated as a result of violence in some form. Calk wounds which penetrate the tissues in the immediate region of the lower portion of the external part of the femerotibial capsule sometimes result in open joint because of tissue necrosis resulting from the introduction of infection. Contused wounds sometimes destroy the skin and fascia over large areas on the lateral patellar region and because of subsequent sloughing of tissue due to infection as well as to the manner in which such wounds are inflicted, septic arthritis subsequently occurs. Penetrant wounds, such as may be caused by a fork tine may not result in infection; if infectious material is introduced an infectious arthritis does not necessarily follow, though such cases should be considered as serious from the outset. Symptomatology.--The pathognomonic symptom of open stifle joint is the profuse escape of synovia, indicating perforation of the synovial capsule; by means of a probe the wound may be explored in a way that will clearly reveal the nature of the injury. After a few days have elapsed in cases where considerable infection has taken place, there is manifestation of pain as in all cases of infective arthritis. Hughes[48] gives an excellent description of the clinical aspect of arthritis which applies here: