CASE 1.--Litharge and blast-furnace worker. Employed in lead works, where a large number of different metallurgical processes associated with the recovery of lead from the ore were carried on. Double wrist-drop, existing for eight years, untreated until some four years after paralysis took place, when slight improvement occurred. The electrical reactions show that the extensor communis digitorum on the right side is completely degenerated, whilst the first interosseous of the right side show reactions of degeneration. On the left side the extensor communis digitorum showed normal but very feeble reaction. This latter point is one of considerable importance if early hæmorrhage accounts for lead paralysis, for if the nerve itself was completely destroyed, or if, as was the case, the muscle appeared completely paralyzed on inspection, obviously the nerve-supply must be completely cut off if the lesion was due to destruction of the nerve of the spinal cord or to the destruction of the lower motor neuron. On the other hand, the presence of small localized fibrillar contraction, found by the galvanic current, together with the presence of a slight reaction to faradism, suggests that some small portion of the nerve has remained unaffected, and that for this reason certain portions of the muscle have not undergone degeneration--a circumstance which can hardly be expected if the cause of the paralysis is in the destruction of the whole of the nerve-supply. ELECTRICAL REACTIONS IN LEAD PARALYSIS. (CASE 1.)