RESPECTED FRIEND, PHILIP E. THOMAS:--Permit us to address you a few lines, and, through you, the committee of the four-yearly meetings of the Society of Friends, in reference to the condition of our suffering friends and brethren still remaining in the country west of the Mississippi. We suppose the committee are already thoroughly acquainted with the means used to decoy those Indians off, in contravention of the instructions of the Government to the removing agent. They were flattered with prospects of almost unbounded prosperity. The country was described as a paradise; and they were told that there friends here, who might now refuse to accompany them, would soon be compelled to follow, and that it would be better to go now and get well started in their improvements, &c., as soon as possible. But, when they reached that country, instead of being a paradise, they found it rather a land of desolation, disease and death, and a large proportion of them are now lying beneath the turf. The survivors are discouraged and broken-hearted, in addition to the sufferings from the disease which has swept off their companions, and they are anxious to return. Application has been made to the Government in their behalf, without obtaining relief, and, from a recent letter from Dr. Wilson, we learn that a similar application to the Legislature of this State is likely to fail. We cannot make any appropriation from our national funds until the meeting of our national council, as a law has been passed which would forbid it, but if we delay till that meeting it will expose our friends to the horrors of the sickly season once more, and doubtless many more of them will perish in consequence. Under these circumstances we see no other resource but to look again to those kind- hearted friends who have done somuch already to relieve us in our distresses. Our obligations are already very great, and we cherish deep feelings of gratitude for past favors. We would not willingly burden your kindness now were it not for the peculiarly difficult and perplexing condition of things just at the present time. But we feel that humanity towards our own people demands of us to make this application in their behalf, as well as of ourselves, for we will always cherish a lively remembrance of your kindness. Wishing you the reward of the benevolent in the great day, we subscribe ourselves your obliged and sincere friends, In presence of Asher Wright, HENRY TWO GUNS, WILLIAM KROUSE, GEORGE X BUTTON, JOHN X GREENBLANKET, ABRAHAM X JOHN, JAMES SPRING, DANIEL TWO GUNS.