SIR:--I transmit herewith a copy of a letter just received from James Cusick, one of the party of the New York Indians removed west last summer by Dr. Hogeboom, from which it appears that there has been much sickness and mortality among those Indians, and that they are in a distressed situation. Mr. Cusick's letter, supported by Capt. Burbanks, is calculated to excite much anxiety on account of these Indians. They were removed contrary to the instructions and expectations of the Department at the time, and their having gone west was not known until they were some distance on the route. There was, consequently, no opportunity for making the requisite preliminary arrangement for their comfort and welfare on their arrival west. After giving you the instructions of June 10th for their subsistance, such had to be left to the judgment and views of duty, under these circumstances, of yourself and the Osage Sub. Agent, under whose immediate supervision they came, in regard to what further required to be done for them. In my letter of the 30th ultimo your attention was especially called to their situation, and no doubt is entertained, that your answers to that communication will show you have done, or caused to be done, all that could be done, under the circumstances, for their relief. Should the amount now remitted not be sufficient to cover the expenses of what you have already done, or what it may be, in your judgment, further requisite to do for them in addition to their subsistance, for which there is a special appropriation, you will please report promptly accordingly, and the necessary funds will be furnished. Funds will also be remitted on account of their subsistance when this office is informed that they are needed. Respectfully, W. MEDILL. THOMAS H. HARVEY, Esq., St. Louis, Mo. MISSIONARY WORK. A RECORD OF THE CONGREGATIONAL CHURCH IN THE TUSCARORA RESERVATION OBTAINED BY INQUIRY. The church in the Tuscarora Reservation was organized in the year 1805, embracing six members only, under the care of the New York Missionary Society. Rev. Elkanah Holmes, first missionary, from 1805 to 1808. Members of the Church--Sacarissa, a Sachem, and his wife; Nicholas Cusick, an interpreter, and his wife; Apollas Jacobs and Mary Pempleton. Rev. Mr. Gray, second missionary, from 1808 to 1813. At first the Indians converted their Council House into one for public worship, and also for school operations, and in time they built a convenient chapel, which was painted red, and was destined to share the same fate as their dwelling houses at the hands of the British Indians in the war of 1812. It was on December 20th, 1813, when they were burned to the ground, in consequence of which the operations of the mission were suspended from 1813 to 1817, when Rev. James C. Crane took charge of the mission until the end of the year 1826. In the year 1821 this mission was transferred from the New York Missionary Society to the United Foreign Mission Society.