Leprosy : $b in its clinical & pathological aspectsHansen, G. Armauer (Gerhard Armauer)
Science
Leprosy : $b in its clinical & pathological aspects
Hansen, G. Armauer (Gerhard Armauer)
Leprosy
_Europhen_ has some resemblance to iodoform, but gives up its iodine
less readily. It is a fine yellow powder, insoluble in water, but
soluble in alcohol, ether, chloroform, and oil. A solution in oil was
used for hypodermic injections: at first 0.015 europhen was injected,
and after a month 0.025. At the end of another month an eruption
developed in one of the patients; in the others no effects were
evident, and thereupon 0.030 was injected. After three weeks an iodine
eczema developed in three of the patients, and a leprous eruption in
another, and consequently no further trials were made. Dr. Julius
Goldschmidt of Madeira, has also used this remedy, and considers one of
his patients as almost cured, while four others remain unchanged.
_Aristol_ was tried by three patients, partly internally, dissolved in
ether, and partly externally, in the form of ointment; the effect was
the same as after the use of iodide of potassium, and it was stopped
after three weeks’ trial.
_Naphthol_ and _Salol_ were tried for a long time, but the effect was
almost _nil_. Salol has also been used by Dr. Lütz in the Sandwich
Islands, and by Surgeon Major Cook in Madras, but though some
amelioration in the condition of the patients has been noted, no case
has been cured.
_Methylene Blue_ was given to one tuberous patient, both internally
and hypodermically. The skin, especially the tubers, became deeply
blue, but a microscopical examination showed the bacilli unaltered. The
treatment was continued from May 20, 1891 till January 30, 1892. Some
tubers diminished a little, but most of them became larger, so that the
disease as a whole grew worse.
_Nerve stretching_ was first tried by Dr. Gerald Bamfert, who stated
that he had done the operation with success on an anæsthetic patient,
in whom both hands were atrophic and sensibility much diminished. The
ulnar nerve was stretched and incised longitudinally. The sensibility
in the right hand re-appeared immediately after the operation; and
after some days the muscular power was almost completely restored. In
three anæsthetic patients in the Lungegaard’s hospital the operation
was performed; the ulnar nerve was stretched and incised along a length
of three to four inches. All went well, only the anæsthesia remained
unchanged; neither sensibility nor muscular power was restored. Dr.
Beaven-Rake, who has done numerous nerve-stretchings in Trinidad, says,
“on the whole the results of nerve-stretching for anæsthesia cannot be
considered satisfactory.”
Dr. Beaven-Rake has also done the operation for pains in the limbs, for
which hypodermic injections of morphine have been successfully used in
the Lungegaard’s hospital.
_Electricity_, both faradic and galvanic, has been used for anæsthetic
leprosy, and electric baths, but no good effect has been attained.
Public-domain text, read in full here on John Shaqi.
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