Life of Elie Metchnikoff, 1845-1916Metchnikoff, Olga
Science
Life of Elie Metchnikoff, 1845-1916
Metchnikoff, Olga
Metchnikoff, Elie, 1845-1916
In 1897 an International Congress took place in Moscow. Metchnikoff
read a paper on the phagocytic reaction against toxins and another
dealing with the whole of the knowledge acquired concerning human
plague. He ended this by a plea in favour of Science, so often accused
of having contributed nothing to the solution of the most important
human problems, particularly ethical ones, and of having, on the
contrary, sanctioned the law of Might by tabulating the laws of the
struggle for existence. Metchnikoff objected that, far from doing
so, Science, by revealing the laws of Nature, applied to humanity
the benefits derived from them, whilst striving to counterbalance
their cruel or harmful effects. The struggle against plague and other
diseases was a concrete example of this, for here medical science
opposed itself to the cruelty of "natural selection." He wound up
his speech by the following words, "Just as, in order to satisfy his
æsthetic tastes, Man revolts against the laws of Nature which creates
races of sterile and fragile flowers, he does not hesitate to defend
the weak against the laws of natural selection. Science has been
faithful to her mission and to her generous traditions. Let her, then,
progress unhindered."
Metchnikoff's friend and companion, M. Nocard, wrote to me concerning
Metchnikoff's paper:
Do not believe a word that Metchnikoff tells you. He had tremendous
success. The somewhat free form of his paper contributed to its
success, as it only made his conviction and enthusiasm more apparent.
Thus the Sibyl on her tripod.
Metchnikoff had at this period a very talented disciple, M. I. Bordet,
who opened a new path by a series of researches of the greatest
importance. He found, among other things, that "the figured elements"
can be destroyed outside the cells, in the humors. Thus, if red blood
corpuscles from one animal are injected into an animal of a different
kind, these globules are destroyed, not within the phagocytes,
but outside them, in the ambient humors. Metchnikoff studied this
phenomenon and proved that the explanation was the same that he had
previously given of Pfeiffer's phenomenon in the case of cholera
vibrions. In Bordet's experiments, the leucocytes which were already
existing in the humors were also damaged by the experimental shock;
but, if this was carefully avoided, the phagocytes, remaining intact,
englobed and digested the injected red corpuscles and no phenomenon
similar to Pfeiffer's took place.
Public-domain text, read in full here on John Shaqi.
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