Louis Pasteur: His Life and LaboursVallery-Radot, René
Science
Louis Pasteur: His Life and Labours
Vallery-Radot, René
Pasteur, Louis, 1822-1895; Scientists -- France -- Biography
This vague theory of viruses was forced to give way before the
multiplied experiments of Pasteur. But before occupying himself with
further discoveries, although it had been irrefutably proved that the
microscopic parasite was the true contagium, it was necessary to throw
light upon the facts, mainly accurate, which had been announced by
Jaillard and Leplat, and to bring them into harmony with the facts, not
less certain, which had been advanced by Davaine. The rabbits which
Jaillard and Leplat had inoculated with a drop of the blood of a cow or
sheep stricken with splenic fever, died rapidly, and the blood of these
rabbits was shown to be also virulent. It was sufficient to inoculate
other rabbits with a very minute quantity to cause their death. But
Jaillard and Leplat affirmed that the examination of that blood did not
reveal the existence of any microscopic organisms. Paul Bert, on his
part, had succeeded in destroying the bacteria by compressed oxygen,
and yet the virulence had continued.
Were there, then, two kinds of virus? What escape was there from this
darkness? A new light suddenly began to dawn. Pasteur had already some
years previously demonstrated that the animal body is sealed against
the introduction of lower organisms--that in the blood, the urine, the
muscles, the liver, the spleen, the kidneys, the brain, the marrow,
and the nerves, in a normal state, no germ is found, or particle of
any kind, known or unknown, which could be transformed into bacteria,
vibrios, monads, or microbes. The intestinal canal alone is filled
with matters associated with a host of germs and living products in
process of development, and in divers states of physiological action.
Not only is its temperature favourable to the life of infusoria,
but it receives incessantly matters charged with the germs of these
microscopic organisms. To the upper portions of the canal the air
still has access, so that even in the stomach aerobic microbes may be
found, but in the lower parts of the intestinal canal oxygen is absent,
and only anaerobic microbes can be developed there. Although the life
exerted in the mucous surface of the intestines opposes itself to the
passage of those little organisms into the interior of the body, this
ceases to be the case after death. There is no longer any obstacle to
arrest or prevent them from acting according to the respective laws of
their evolution and of the decomposing influence which belongs to them.
It is by anaerobic organisms, in fact, that the putrefaction of dead
bodies is begun. They penetrate into the organs and into the blood as
soon as this liquid is deprived of oxygen; and it is not long before
this happens, the oxygen fixed in the globules being soon consumed. In
the body of an animal which has died of splenic fever, putrefaction is
still more rapid, because, through the action of the disease, the blood
is already in a great degree deprived of oxygen at the time of death.
Public-domain text, read in full here on John Shaqi.
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