There was a burst of enthusiasm at these truly marvellous results. The veterinary surgeons especially, who had received with entire incredulity the anticipations recorded in the programme of the experiments, who in their conversations and in their journals had declared very loudly that it was difficult to believe in the possibility of preparing a vaccine capable of triumphing over such deadly diseases as fowl cholera and splenic fever, could not recover from their surprise. They examined the dead, they felt the living. 'Well,' said M. Bouley to one of them, 'are you convinced? There remains nothing for you to do but to bow before the master,' he added, pointing to Pasteur, 'and to exclaim-- "I see, I know, I believe, I am undeceived."' Having suddenly become fervent apostles of the new doctrine, the veterinary surgeons went about proclaiming everywhere what they had seen. One of those who had been the most sceptical carried his proselytising zeal to such a point that he wished to inoculate himself. He did so with the two first vaccines, without other accident than a slight fever. It required all the efforts of his family to prevent him from inoculating himself with the most virulent virus. An extraordinary movement was everywhere produced in favour of vaccination. A great number of agricultural societies wished to repeat the celebrated experiment of Pouilly-le-Fort. The breeders of cattle overwhelmed Pasteur with applications for vaccine. Pasteur was obliged to start a small manufactory for the preparation of these vaccines in the Rue Vauquelin, a few paces from his laboratory. At the end of the year 1881, he had already vaccinated 33,946 animals. This number was composed of 32,550 sheep, 1,254 oxen, 142 horses. In 1882, the number of animals vaccinated amounted to 399,102, which included 47,000 oxen and 2,000 horses. In 1883, 100,000 animals were added to the total of 1882. From the commencement of the practical application of this new system, the results were topical. Among flocks where half had been vaccinated and the other half not vaccinated--all the animals continuing to live together--the mortality from splenic fever in 1881 was ten times less in the vaccinated sheep than in the non-vaccinated, being 1 in 740 as against 1 in 78; and in cows and oxen fourteen times less, being 1 in 1,254 against 1 in 88. In 1882 also, the mortality was ten times greater among the non-vaccinated than among the vaccinated animals.