The seminal vesicles are plainly felt indurated, nodular and distended with fluid. In a large proportion of cases the repeated congestion causes a veritable seminal vesiculitis. This inflammation is not seldom extended to the ejaculatory ducts and occludes the same. Through this occlusion spermatic colic, i. e., a severe pain in the region of the vesicles, often seizes the patient, especially after some sexual excitement, as dancing, caressing, and even flirting. After such excitement a dull pain in the region of the prostate and in the perineum as well as in the testicles, spermatic cords and in the rectum is very annoying to the patient. Ejaculation often removes these pains. For that reason the patient tries to relieve himself from the painful sensations by masturbation. Ejaculation also removes the irritations of the thighs, hips, anus, hypogastric region and in the smalls of the back. The entire urethra is often in a state of hyperaesthesia and paraesthesia, and the prostatic portion shows congestion and not seldom an inflammation of the mucous membrane. Especially the colliculus is often in a severe inflammatory condition. There is thickening sponginess or puffiness of the parts immediately involving the ejaculatory ducts. The urethra manifests great sensibility. The introduction of a bougie produces unbearable pains. The withdrawal of the sound is often followed by several drops of blood. This hypertrophy and inflammation of the colliculus seminalis is the cause of the ejaculatio praecox in the beginning of the disease. Later on the condition provokes weak erections and finally ejaculation with flaccid member before entrance into the vagina. The irritation of the urethra causes hypersecretion of the glands of Littré and Cowper which is manifested by the so-called urethrorrhoea. In urethrorrhoea the secretion is thin, transparent, perfectly clear and sticky. The secretion has no spermatic odor and does not stain the linen, but stiffens it. It is seen as a drop in the morning at awakening with an erection. The drop is sticky and tenacious. The meatus urethrae sticks together. The drop is not rarely found in healthy men after violent and continuous erections. The secretions show under the microscope nothing beyond free mucous and columnar and pavement epithelia. Besides the hypersecretion of the urethral glands, there is also a hypersecretion of the prostate, especially in patients who have indulged in excesses in masturbation and in onanism (coitus interruptus). Masturbation as well as onanism do not give the same satisfaction as normal coition, hence constant hankering for more and overindulgence. Prostatorrhoea is often found after gonorrhoea, when the yellowish drop gradually becomes whitish, flocculent, and finally a colorless watery drop of clear, slightly viscid fluid. It is best seen when the lips of the meatus are held apart.