Miss X., a school teacher, over thirty years of age, was always chaste and indifferent not only to any carnal pleasure, but also to male company. On account of a uterine fibroid, a total extirpation of uterus and ovaries was performed. Since the operation the patient complains of great sexual excitability she had never experienced before the operation. She is so excited sexually that she is possessed of the almost imperative impulse to kiss every male person she meets on the street, and but for her position, she would have long ago yielded to this impulsive desire. In another case of diminution of the potency of libido, only uterine inflammation and pregnancy could be discovered. Mrs. M., thirty-five years of age, four months married, had always suffered pain in the back during menstruation. The patient complains that she only experienced libido twice since she has been married. Since the last experience in the first weeks of her married life, she has no pleasure at all. Coition, though not painful, causes her a disagreeable feeling. An examination revealed anteflexio uteri, enlargement and catarrh of the cervix, erosions and a three months’ pregnancy. In the following case castration caused inability to experience libido. Mrs. M., thirty-five years of age, for the last fifteen years married but sterile. When she was only two years married she began to suffer from attacks of headaches and vomiting, which repeated almost every other day. Her menstruation was regular. After having tried all the stomach specialists in the city without finding any relief from the vomiting spells, she consulted a gynaecologist, and he promptly found an ovary to be the cause of all her troubles. She had been previously operated upon for gall stones, which were not found and for appendicitis, when the presumably diseased appendix was removed. She now submitted to ovariectomy on the left side. Three months after the operation the vomiting spells returned, and she submitted again to a removal of the right ovary. But even this double castration did not relieve her. When she first consulted the author she was still suffering from these spells, especially before menstruation, which is still present although irregular. The patient declares that previous to the ovariotomies she experienced full libido and was able to induce orgasm. After the second ovariotomy this potency was lost. She gets excited during coition, but the orgasm cannot be produced. The following day she feels nervous and weak. In another case of impotence of libido nothing else but anteflexio could be discovered.