The number of women afflicted with the anomaly of impotence of libido is considerable. It is claimed by many authorities that ten to twenty per cent. of all women are afflicted with this anomaly. The symptoms of total anaesthesia are subjective and objective. There is first the statement of the husband about his wife’s indifference and coldness during the conjugal embrace. The woman complains of lack of orgasm and ejaculation and of the immediate flowing off of the sperma after coition. The peristaltic contractions of the vaginal walls, beginning at the vaginal orifice, and the aspirating movements of the uterus, as they take place in the normal woman, during the orgasm, are missing here. Hence the sperma is immediately discharged from the vagina. One of the most conspicuous objective symptoms is a relaxation of the entire genital tract. The glans of the clitoris is often undeveloped or wholly adherent to the prepuce. In some women old lacerations of the perineum are present. The genital muscles, the levator ani and constrictor cunni as well as the perineum, are languid and withered. The mucous membrane of the entire genital tract is in a state of hypersecretion, as in true chronic inflammations. The vagina is wide and flabby, the walls are lacking elasticity. The portio vaginalis uteri is flabby and pointed. The uterine walls are weak and soft, and the cavity is wide. The uterus is extremely movable and generally lies in retropositio, the relaxation of the uterine ligaments allowing it to fall downward and backward. The patient’s general health is often poor, she is anemic, nervous and weak. Sometimes there is only hypoplasia of some of the genital organs, otherwise the woman enjoys good health. Women suffering from anaesthesia may without sacrifice refuse their favors to their husbands and render them submissive to their will and henpecked. Single women, having no pleasure in and hence no desire for conjugation, if they are not induced to give themselves for pecuniary considerations, easily remain virtuous and seem to be very proud of this enforced purity. Even among married women there are wives who pride themselves on repugnance or distaste for their conjugal obligations. They speak of their coldness and the calmness of their senses as though they were not defects but great virtues. Yet the sour, shallow, sexless shrew is surely an imposture as a wife. Her marriage is nothing else but a fraud. In congenital anaesthesia the therapy is valueless, although electricity by Apostoli’s method and massage may be tried in uterus infantilis and in undeveloped ovaries. In prolific women the only advice the physician may give is that, in harmony with Ovid’s recommendation, “Tu quoque cui Veneris sensum natura negavit, “Dulcia mendaci gaudia finge sono.”