The frequent exercise actionis conjungendi leads directly to anaemia, malnutrition, asthenia of the muscles and nerves, and mental exhaustion. Immoderate persons are pale and have long, flabby and sometimes tense features. They are melancholic and not fit for any difficult and continued bodily or mental work. They possess very little power of resistance. The patients suffer from aboulia or inability to concentrate their minds upon any subject. There is a certain dysaesthesia or hyperaesthesia of the senses, especially against noise and light. Insomnia is very frequently complained of. Cephalalgia and vertigo is a frequent occurrence. The patients have a feeling of anxiety in stomach and in heart-regions. Anorexia, or loss of appetite, is often met with. Besides, the patient suffers from nervous dyspepsia and constipation which not seldom alternates with diarrhoea. There is often found tachycardia and an arythmic or intermittent pulse. Sometimes asthma and coughing are complained of. The patients feel fatigued at the least exertion. The most annoying symptom is pollakiuria and cystic tenesmus. In men pains in the back are radiating to the legs and to the inguinal and spermatic-cord regions; in women coccygodynia is often encountered. These effects frequentis commixtionis are often seen in men and women after a certain period of married life has elapsed. Apart from the bad effects upon the general health of the man and woman, excesses in venere cause various local disturbances. Too frequent sexual excitement retards the orgasm or makes it impossible. The detumescence that normally occurs after ejaculation does not take place. The genital organs remain thus in a certain state of congestion which causes chronic inflammations, such as prostatitis, vesiculitis, orchitis or urethritis in men, and vulvitis, vaginitis, endometritis, metritis, salpingitis, ovaritis or peri- and parametritis in women. The habitual congestion of the uterus causes the tissues to become succulent, and the vessels enlarged. It shows, then, all the symptoms of subinvolution, such as menorrhagia, exhaustion and sexual apathy. Sexual excess, as everything else abused, produces satiety and finally indifference. Emptiness in life is then the individual’s lot, and it falls into a state of moral apathy which is characterized by the suspension or complete loss of every sentiment.[CT]