Makers of Modern MedicineWalsh, James J. (James Joseph)
History
Makers of Modern Medicine
Walsh, James J. (James Joseph)
Medicine -- Biography
Pasteur's discovery was much more than a new fact in chemistry and
physics. It was the foundation-stone that was to support the new
science of stereochemistry--the study of the physiochemical
arrangement of atoms within the molecule--that took its rise a few
years later. Much more, it was a great landmark in biology. Pasteur
pointed out that all mineral substances--that is, all the natural
products not due to living energy--have a superposable image and are,
therefore, not dissymmetrical. All the products of vegetable and
animal life are dissymmetrical. All these latter substances turn the
plane of polarization. This is the great fundamental distinction
between organic and inorganic substances--the only one that has
endured thus far in the advance of science. Dissymmetry probably
represents some essential manifestation of vital force. Often there
seem to be exceptions to this law; but careful analysis of the
conditions of the problem shows that they are not real.
{300}
An apparent contradiction, for instance, to this law of demarcation
between artificial products and the results of animal and vegetable
life is presented by the existence in living creatures of substances
like oxalic acid, formic acid, urea, uric acid, creatine, creatinin,
and the like. None of these substances, however, has any effect on
polarized light or shows any dissymmetry in the form of its crystals.
These substances, it must be remembered, are the result of secondary
action. Their formation is evidently governed by the laws which
determine the composition of the artificial products of our
laboratory, or of the mineral kingdom properly so called. In living
beings they are the results of excretion rather than substances
essential to life. The essential fundamental components of vegetables
and animals are always found to possess the power of acting on
polarized light. Such substances as cellulose, fecula, albumin,
fibrin, and the like, never fail to have this power. This is
sufficient to establish their internal dissymmetry, even when, through
the absence of characteristic crystallization, they fail to manifest
this dissymmetry outwardly.
Public-domain text, read in full here on John Shaqi.
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