The inhabitants of the waters seem comparatively secure from human pursuit or interference by the inaccessibility of their retreats, and by our ignorance of their habits--a natural result of the difficulty of observing the ways of creatures living in a medium in which we cannot exist. Human agency has, nevertheless, both directly and incidentally, produced great changes in the population of the sea, the lakes, and the rivers, and if the effects of such revolutions in aquatic life are apparently of small importance in general geography, they are still not wholly inappreciable. The great diminution in the abundance of the larger fish employed for food or pursued for products useful in the arts is familiar, and when we consider how the vegetable and animal life on which they feed must be affected by the reduction of their numbers, it is easy to see that their destruction may involve considerable modifications in many of the material arrangements of nature. The whale does not appear to have been an object of pursuit by the ancients, for any purpose, nor do we know when the whale fishery first commenced.[97] It was, however, very actively prosecuted in the Middle Ages, and the Biscayans seem to have been particularly successful in this as indeed in other branches of nautical industry.[98] Five hundred years ago, whales abounded in every sea. They long since became so rare in the Mediterranean as not to afford encouragement for the fishery as a regular occupation; and the great demand for oil and whalebone for mechanical and manufacturing purposes, in the present century, has stimulated the pursuit of the "hugest of living creatures" to such activity, that he has now almost wholly disappeared from many favorite fishing grounds, and in others is greatly diminished in numbers.