When a patient or pupil is placed in the position of mechanical advantage I have so often had occasion to refer to, the manipulator can secure the maximum movement of the abdominal viscera in strict accordance with the laws of nature and will obtain at the same time a maximum functioning of all the internal organs. In this way foreign accumulations are dissipated, constipation is relieved, and the more or less collapsed viscera—the cause of all the trouble—are restored to their proper places and resume their natural functions. All these things, it will be seen, are essential factors in the prevention and cure of appendicitis, and I may add that the application of these principles in a very large number of cases in which an operation has been medically advised has conclusively demonstrated their value to the individual and to the race. Appendicitis, like influenza, is probably almost an impossibility in the natural state; it is one of the results of civilisation and subconsciously controlled mechanisms, and is possible only through the conditions we have developed; and these adventitious troubles and ailments will continue to appear and to do their work of destruction until some general recognition is made of the necessity for substituting conscious control for the partly superseded forces which in a wild state render these ailments impossible. III. “_What are the outward signs of improvement to be noted during treatment?_” The signs of improvement are manifold and they necessarily vary according to the nature of the original defect, but I will set out here some of the more characteristic, such as occur in generally typical cases. We see, in the first place, that the characteristic defects of the body, whether displacements of some part or parts of the muscular mechanism (in some cases even displacement of the bones), or defects of pose which throw some unusual strain upon a muscle, or, more commonly, a group of muscles not intended to take such strain, all have some correlated defects, which may be observed by the instructed as certain visible peculiarities and abnormalities. And we must draw particular attention in this connexion to the fact that these outer signs are _correlated_ with the inner defects. Neither outer sign nor inner defect is from one point of view the _result_ one of the other. The original cause is some faulty or imperfect co-ordination or conception of function; the inner defect and outer sign-mark are equally a consequence as they are to us an index.