Manual of Surgery Volume First: General Surgery. Sixth Edition.Thomson, Alexis
Science
Manual of Surgery Volume First: General Surgery. Sixth Edition.
Thomson, Alexis
Surgery
_The Alleged Increase of Cancer._--Regarding the alleged increase of
cancer, it may be pointed out that it is impossible to ascertain how
much of the apparent increase is due to more accurate diagnosis and
improved registration. It is probable also that some increase has taken
place in consequence of the increased average duration of life; a larger
proportion of persons now reach the age at which cancer is frequent.
_The prognosis_ largely depends on the variety of cancer and on its
situation. Certain varieties--such as the atrophic cancer of the breast
which occurs in old people, and some forms of cancer in the rectum--are
so indolent in their progress that they can scarcely be said to shorten
life; while others--such as the softer varieties of mammary cancer
occurring in young women--are among the most malignant of tumours. The
mode in which cancer causes death depends to a large extent upon its
situation. In the gullet, for example, it usually causes death by
starvation; in the larynx or thyreoid, by suffocation; in the intestine,
by obstruction of the bowels; in the uterus, prostate, and bladder, by
hæmorrhage or by implication of the ureters and kidneys. Independently
of their situation, however, cancers frequently cause death by giving
rise to a progressive impairment of health known as the _cancerous
cachexia_, a condition which is due to the continued absorption of
poisonous products from the tumour. The patient loses appetite, becomes
emaciated, pale, and feverish, and gradually loses strength until he
dies. In many cases, especially those in which ulceration has occurred,
the addition of pyogenic infection may also be concerned in the failure
of health.
_Treatment._--Removal by surgical means affords the best prospect of
cure. If carcinomatous disease is to be rooted out, its mode of spread
by means of the lymph vessels must be borne in mind, and as this occurs
at an early stage, and is not evident on examination, a wide area must
be included in the operation. The organ from which the original growth
springs should, if practicable, be altogether removed, because its lymph
vessels generally communicate freely with each other, and secondary
deposits have probably already taken place in various parts of it. In
addition, the nearest chain of lymph glands must also be removed, even
though they may not be noticeably enlarged, and in some cases--in cancer
of the breast, for example--the intervening lymph vessels should be
removed at the same time.
The treatment of cancer by other than operative methods has received a
great deal of attention within recent years, and many agents have been
put to the test, _e.g._ colloidal suspensions of selenium, but without
any positive results. Most benefit has resulted from the use of radium
and of the X-rays, and one or other should be employed as a routine
measure after every operation for cancer.
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